Details of the Target

General Information of Target

Target ID LDTP19547
Target Name Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323
Synonyms
Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323; dUTPase-like protein
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MALLITPAGVATVNRHSTIPSDTHTSREKPRFHKPCRNDLESLLSEGRLDTSVQTPCPQH
PHTQLSCEPQPLEHSSCLSTCLAGCFLPVPSSPHTHPLLPGSRWLPPPLALLMGTLSPGL
AVKPSWVPRFPLLARQSPATSVGMPLSAATQPGSVGRLHFPKLRSSSPFSGHSDENKATG
QGRENRDQPQRPSHLCECPEAAKQSATNGVAETNRSVFPLGSEARSLSLRRQESQPHSGS
SRRESVSCSPSFWCCWQPLAFLTCGCAAPISVPGVTRPSPRPCCVSPPLVRLQSLGLGPT
QI
Target Bioclass
Enzyme
Family
DUTPase family
Uniprot ID
Q6ZN92

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY-1
 Probe Info  		E130(0.00); K132(0.00)  LDD0246  [1]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.