Details of the Target

General Information of Target

Target ID LDTP19513
Target Name Protein FAM199X (FAM199X)
Gene Name FAM199X
Gene ID 139231
Synonyms
CXorf39; Protein FAM199X
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLRRGHLAFRDVAIEFPQEEWKCLDPAQRTLYREVMVENYRNLVFLGICLPDLSVISMLE
QRRDPRNLQSEVKIANNPGGRECIKGVNAESSSKLGSNAGNKSLKNQLGLTFQLHLSELQ
LFQAERNISGCKHVEKPINNSLVSPLQKIYSSVKSHILNKYRNDFDDSPFLPQEQKAQIR
EKPCECNEHGKAFRVSSRLANNQVIHTADNPYKCNECDKVFSNSSNLVQHQRIHTGEKPY
KCHECGKLFNRISLLARHQRIHTGEKPYKCHECGKVFTQNSHLANHHRIHTGEKPYKCNE
CGKVFNRNAHLARHQKIHSGEKPYKCKECGKAFSGGSGLTAHLVIHTGEKLYKCNKCGKV
FNRNAHLTRHQRIHTGEKPYECKECGKVFRHKFCLTNHHRMHTGEQPYKCNECGKAFRDC
SGLTAHLLIHTGEKPYKCKECAKVFRHRLSLSNHQRFHTGEKPYRCDECGKDFTRNSNLA
NHHRIHTGEKPYKCSECHKVFSHNSHLARHRQIHTGEKSYKCNECGKVFSHKLYLKKHER
IHTGEKPYRCHECGKDFTRNSNLANHHRIHTGEKPYR
Target Bioclass
Other
Family
FAM199 family
Uniprot ID
Q6PEV8
Ensemble ID
ENST00000493442.2
HGNC ID
HGNC:25195

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
BT549 SNV: p.R198W .
CAL51 SNV: p.S281G .
EFO27 SNV: p.R61H .
LS123 SNV: p.S88F .
MCC13 SNV: p.H60Y .
RL952 SNV: p.R357Q .
SNU869 SNV: p.P253T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C235(1.05)  LDD1492  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 HEK-293T C235(1.05)  LDD1492  [1]
 LDCM0023  KB03 HEK-293T C235(0.93)  LDD1497  [1]
 LDCM0024  KB05 HEK-293T C235(1.00)  LDD1502  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402