Details of the Target

General Information of Target

Target ID LDTP19512
Target Name Zinc finger protein 880 (ZNF880)
Gene Name ZNF880
Gene ID 400713
Synonyms
Zinc finger protein 880
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRRGLVAGPDLEYFQRRYFTPAEVAQHNRPEDLWVSYLGRVYDLTSLAQEYKGNLLLKP
IVEVAGQDISHWFDPKTRDIRKHIDPLTGCLRYCTPRGRFVHVPPQLPCSDWANDFGKPW
WQGSYYEVGRLSAKTRSIRIINTLTSQEHTLEVGVLESIWEILHRYLPYNSHAASYTWKY
EGKNLNMDFTLEENGIRDEEEEFDYLSMDGTLHTPAILLYFNDDLTEL
Target Bioclass
Transcription factor
Uniprot ID
Q6PDB4
Ensemble ID
ENST00000344085.9
HGNC ID
HGNC:37249

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
42MGBA SNV: p.Q28Ter .
AN3CA SNV: p.V153A .
COLO829 SNV: p.P169Q .
HCT116 Deletion: p.K537NfsTer60 .
HCT15 SNV: p.R257Ter .
IGROV1 SNV: p.G47Ter .
MCC26 SNV: p.Q455Ter; p.H498Y .
NCIH196 SNV: p.E300D .
NCIH716 SNV: p.F529S .
RL952 Deletion: p.K537NfsTer60 .
SNGM Deletion: p.K537NfsTer60 .
SW1271 SNV: p.I261T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K238(0.00); K241(0.00); Y240(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010