Details of the Target
General Information of Target
| Target ID | LDTP19511 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cytochrome b5 domain-containing protein 1 (CYB5D1) | |||||
| Gene Name | CYB5D1 | |||||
| Gene ID | 124637 | |||||
| Synonyms |
Cytochrome b5 domain-containing protein 1 |
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| 3D Structure | ||||||
| Sequence |
MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEE
TVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFT WRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV LPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGV LVRIVLCALRGGLQQ |
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| Target Bioclass |
Other
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| Family |
Cytochrome b5 family
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| Subcellular location |
Cytoplasm, cytoskeleton, cilium axoneme
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| Function | Radial spoke stalk protein that binds heme under oxidizing conditions. Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
Acrolein Probe Info |
 |
N.A. | LDD0217 | [1] | |