Details of the Target

General Information of Target

Target ID LDTP19500
Target Name WD repeat-containing protein 93 (WDR93)
Gene Name WDR93
Gene ID 56964
Synonyms
WD repeat-containing protein 93
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MWPPCGTLRTLALARSRGARACSGDGGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKM
KNFITCFKDPQFLVTFFSRLRPNRSGRYEAAFPFLSPCGRERNFLRCEDRPVVFTHLLTA
DHGPPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACF
EYGPGAPALPSHVRWQGRRLALTMDLAPLLLAARSP
Target Bioclass
Enzyme
Uniprot ID
Q6P2C0
Ensemble ID
ENST00000268130.12
HGNC ID
HGNC:26924

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 SNV: p.L496I .
A101D SNV: p.P257L .
A431 SNV: p.E85K .
COLO792 SNV: p.R5K .
HT115 SNV: p.F585I .
NCIH1299 SNV: p.W138L .
NCIH2286 SNV: p.A110G .
RL952 SNV: p.G503R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0227  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa N.A.  LDD0227  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.