Details of the Target

General Information of Target

Target ID LDTP19488
Target Name G antigen 2A (GAGE2A)
Gene Name GAGE2A
Gene ID 729447
Synonyms
GAGE2; G antigen 2A; GAGE-2A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVR
SQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRH
CRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPT
SPATPRPSSASGGFVDSSEGSAGSGPLWCSAESCLPSTRRRPSLSQERLAGAGTPLPWAS
SSPTSTPALGGRRGLLRCRSQPCVLSGKRSRRKRRREEDARWTRPSLDFLKMTQTLKNSK
SLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLRTSPVHPNLWASRESVT
SDGSRRSSGDPRDGDSVGEEGVFPRARWELDLEQIENN
Target Bioclass
Other
Family
GAGE family
Uniprot ID
Q6NT46
Ensemble ID
ENST00000362097.2
HGNC ID
HGNC:4099

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-475
 Probe Info  		Y16(1.07)  LDD0264  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0116  HHS-0101 DM93 Y16(1.07)  LDD0264  [1]
 LDCM0117  HHS-0201 DM93 Y16(1.21)  LDD0265  [1]
 LDCM0118  HHS-0301 DM93 Y16(1.27)  LDD0266  [1]
 LDCM0119  HHS-0401 DM93 Y16(1.59)  LDD0267  [1]
 LDCM0120  HHS-0701 DM93 Y16(2.05)  LDD0268  [1]

References

1 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.