Details of the Target

General Information of Target

Target ID LDTP19359
Target Name FERM and PDZ domain-containing protein 3 (FRMPD3)
Gene Name FRMPD3
Synonyms
KIAA1817; FERM and PDZ domain-containing protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSHTEVKLKIPFGNKLLDAVCLVPNKSLTYGIILTHGASGDMNLPHLMSLASHLASHGFF
CLRFTCKGLNIVHRIKAYKSVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHIEPDDG
DDFVRGLICISYPLHHPKQQHKLRDEDLFRLKEPVLFVSGSADEMCEKNLLEKVAQKMQA
PHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITEMDKKCH
Target Bioclass
Other
Uniprot ID
Q5JV73
Ensemble ID
ENST00000276185.9
HGNC ID
HGNC:29382

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C1198(2.97)  LDD3342  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Lu-65 C1198(1.24)  LDD2447  [1]
 LDCM0023  KB03 Lu-65 C1198(1.00)  LDD2864  [1]
 LDCM0024  KB05 NCI-H1155 C1198(2.97)  LDD3342  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840