Details of the Target

General Information of Target

Target ID LDTP19341
Target Name T-complex protein 11-like X-linked protein 2 (TCP11X2)
Gene Name TCP11X2
Gene ID 100996648
Synonyms
T-complex protein 11-like X-linked protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIAPSPKSSEEEGQKDEEVLQGEQGDFNDNDTEPENLGHRPLLMDSEDEEEEEKRSSDSD
YEQAKAKYSDMSPVYRDKSGSGPTQDINTILLTSAQLSSDVGVETPKQEFDIFGAVPFFA
VCAQQPQQEKNEKSLPQHRFPATGLQQEEFDVFTKAPFSKKVNVQECHAVGPETHPKSID
IFDFTPFQPFLTSTSKSESNEDLFGLVPFEEIMGSQQQKVKQRSLQKLSSRQRRTKQDMS
KSNGKRHHGTPTSKKKTLKPTYRTPERARRHKKVGRRVSQTSNEFVTISDSKENIGAAVT
DGNDRGNVLQLEESLLDPFGAKPFHPPDLSWHPLHQGLNDIRADHNTVLPKQPRQNSLHG
SFHSADVLTMDDFGAMPFTELVVQSITLQQSQQSQPVELDPFGAAPFPSKQ
Target Bioclass
Other
Family
TCP11 family
Uniprot ID
Q5H9J9
Ensemble ID
ENST00000642911.3
HGNC ID
HGNC:48335

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
BTD
 Probe Info  		C325(1.08)  LDD2098  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C325(1.08)  LDD2098  [1]

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761