Details of the Target

General Information of Target

Target ID LDTP19337
Target Name Probable inactive ribonuclease-like protein 12 (RNASE12)
Gene Name RNASE12
Gene ID 493901
Synonyms
Probable inactive ribonuclease-like protein 12
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPAVTRLLFLQLVLGPTLVMDIKMQIGSRNFYTLSIDYPRVNYPKGFRGYCNGLMSYMR
GKMQNSDCPKIHYVIHAPWKAIQKFCKYSDSFCENYNEYCTLTQDSLPITVCSLSHQQPP
TSCYYNSTLTNQKLYLLCSRKYEADPIGIAGLYSGI
Target Bioclass
Enzyme
Family
Pancreatic ribonuclease family
Subcellular location
Secreted
Function Does not exhibit any ribonuclease activity.
Uniprot ID
Q5GAN4
Ensemble ID
ENST00000556526.1
HGNC ID
HGNC:24211

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		H66(0.00); H70(0.00)  LDD0233  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa H66(0.00); H70(0.00)  LDD0233  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.