General Information of Target

Target ID LDTP19110
Target Name LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3)
Gene Name LIMS3
Gene ID 100288695
Synonyms
PINCH3; LIM and senescent cell antigen-like-containing domain protein 3; Particularly interesting new Cys-His protein 3; PINCH-3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIFSMLRKLPKVTCRDVLPEIRAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREV
RVKCVKALKGLYGNRDLTARLELFTGCFKDWMVSMIMDREYSVAVEAVRLLILILKNMEG
VLMDVDCESVYPIV
Target Bioclass
Other
Subcellular location
Cytoplasm
Uniprot ID
P0CW19
Ensemble ID
ENST00000437679.3
HGNC ID
HGNC:30047

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C200(1.28)  LDD3325  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 42-MG-BA C200(1.61)  LDD2244  [1]
 LDCM0023  KB03 42-MG-BA C10(3.19); C200(2.40)  LDD2661  [1]
 LDCM0024  KB05 UACC257 C200(1.28)  LDD3325  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840