Details of the Target

General Information of Target

Target ID LDTP19013
Target Name Melanoma-associated antigen B3 (MAGEB3)
Gene Name MAGEB3
Gene ID 4114
Synonyms
Melanoma-associated antigen B3; MAGE-B3 antigen
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADEEKLPPGWEKRMSRPSGRGYYFNHITNPSQWERPSGNSSSGGKIWQGEPARVRRSHL
LVKPVKAALDLAAGNHPDQGGGPGADQRLHPEDQGRREGL
Target Bioclass
Other
Uniprot ID
O15480
Ensemble ID
ENST00000361644.4
HGNC ID
HGNC:6810

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C148(1.40)  LDD3376  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 D283 Med C148(1.27)  LDD2312  [1]
 LDCM0023  KB03 Daoy C148(2.12)  LDD2731  [1]
 LDCM0024  KB05 ONS-76 C148(1.40)  LDD3376  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840