Details of the Target

General Information of Target

Target ID LDTP18996
Target Name POTE ankyrin domain family member B2 (POTEB2)
Gene Name POTEB2
Gene ID 100287399
Synonyms
POTE ankyrin domain family member B2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MCLYCWDIEPSQVNPEGPRQHHPSEVTERQLANKRIQNMQHLKKEKRRLNKRFSRPSPIP
EPGLLWSS
Target Bioclass
Other
Family
POTE family
Uniprot ID
H3BUK9
Ensemble ID
ENST00000454856.4
HGNC ID
HGNC:48327

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C197(1.90)  LDD3466  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 KYSE-180 C197(3.26)  LDD2435  [1]
 LDCM0023  KB03 KYSE-180 C197(6.22)  LDD2852  [1]
 LDCM0024  KB05 TF-1 C197(1.90)  LDD3466  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840