Details of the Target

General Information of Target

Target ID LDTP18975
Target Name Uncharacterized membrane protein C3orf80 (C3orf80)
Gene Name C3orf80
Gene ID 401097
Synonyms
Uncharacterized membrane protein C3orf80
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNALDGVPFKLPKGFVIGTEPLPGPELSVPACGEVLLGSMHDFSLERTALFWVEAAGQGP
SPYQCGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQERPEEEGEDEAEASSGSE
EEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGLRG
HRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTVASLSPYTC
LPPLGGAPQPLNPHKSHPDTAADLLSALSQEEQDLIGPVVALGYPLRRAIIALQKTGRQS
LSQFLSYLSACDRLLRQGYEEGLVDEAMEMFQFSESQAGEFLRLWEQFSDMGFQQDRIKE
VLLVHGNRREQALEELVACAQ
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
F5H4A9
Ensemble ID
ENST00000326474.5
HGNC ID
HGNC:40048

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C177(1.39)  LDD1509  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0226  AC11 HEK-293T C177(1.39)  LDD1509  [1]
 LDCM0278  AC19 HEK-293T C177(1.54)  LDD1517  [1]
 LDCM0287  AC27 HEK-293T C177(1.17)  LDD1526  [1]
 LDCM0290  AC3 HEK-293T C177(0.89)  LDD1529  [1]
 LDCM0296  AC35 HEK-293T C177(1.22)  LDD1535  [1]
 LDCM0305  AC43 HEK-293T C177(1.29)  LDD1544  [1]
 LDCM0314  AC51 HEK-293T C177(1.48)  LDD1553  [1]
 LDCM0322  AC59 HEK-293T C177(1.20)  LDD1561  [1]
 LDCM0406  CL19 HEK-293T C177(1.38)  LDD1610  [1]
 LDCM0420  CL31 HEK-293T C177(1.17)  LDD1624  [1]
 LDCM0433  CL43 HEK-293T C177(1.11)  LDD1637  [1]
 LDCM0446  CL55 HEK-293T C177(1.33)  LDD1649  [1]
 LDCM0459  CL67 HEK-293T C177(1.25)  LDD1662  [1]
 LDCM0462  CL7 HEK-293T C177(1.33)  LDD1665  [1]
 LDCM0472  CL79 HEK-293T C177(1.35)  LDD1675  [1]
 LDCM0486  CL91 HEK-293T C177(1.16)  LDD1689  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402