General Information of Target

Target ID LDTP18887
Target Name Putative fatty acid-binding protein 5-like protein 3 (FABP5P3)
Gene Name FABP5P3
Synonyms
FABP5L3; Putative fatty acid-binding protein 5-like protein 3; Fatty acid-binding protein 5 pseudogene 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDRAKQQQALLLLPVCLALTFSLTAVVSSHWCEGTRRVVKPLCQDQPGGQHCIHFKRDNS
SNGRMDNNSQAVLYIWELGDDKFIQRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQG
VLWLSIGGEVLDIVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMM
YTTIFQITVNLGPEDWKPQTWDYGWSYCLAWGSFALCLAVSVSAMSRFTAARLEFTEKQQ
AQNGSRHSQHSFLEPEASESIWKTGAAPCPAEQAFRNVSGHLPPGAPGKVSIC
Target Bioclass
Other
Family
Calycin superfamily, Fatty-acid binding protein (FABP) family
Function High specificity for fatty acids.
Uniprot ID
A8MUU1
HGNC ID
HGNC:22573

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C87(1.28)  LDD3333  [1]
NAIA_5
 Probe Info 
N.A.  LDD2223  [2]
HHS-465
 Probe Info 
N.A.  LDD2240  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 697 C87(1.25)  LDD2245  [1]
 LDCM0023  KB03 697 C87(1.65)  LDD2662  [1]
 LDCM0024  KB05 MOLM-13 C87(1.28)  LDD3333  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
3 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010