Details of the Target

General Information of Target

Target ID LDTP18759
Target Name G antigen 12H (GAGE12H)
Gene Name GAGE12H
Gene ID 729442
Synonyms
G antigen 12H; GAGE-12H
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MADRGPWRVGVVGYGRLGQSLVSRLLAQGPELGLELVFVWNRDPGRMAGSVPPSLQLQNL
AALGERRPDLVVEVAHPKIIHESGAQILRHANLLVGSPSALSDQTTERQLLEASQHWDHA
VFVARGALWGAEDIRRLDAAGGLRSLRVTMATHPDGFRLEGPLAAAHSPGPCTVLYEGPV
RGLCPFAPRNSNTMAAAALAAPSLGFDGVIGVLVADTSLTDMHVVDVELSGPRGPTGRSF
AVHTRRENPAEPGAVTGSATVTAFWQSLLACCQLPSRPGIHLC
Target Bioclass
Other
Family
GAGE family
Uniprot ID
A6NDE8
Ensemble ID
ENST00000381722.2
HGNC ID
HGNC:31908

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-475
 Probe Info  		Y10(0.94)  LDD0264  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0116  HHS-0101 DM93 Y10(0.94)  LDD0264  [1]
 LDCM0118  HHS-0301 DM93 Y10(1.13)  LDD0266  [1]
 LDCM0119  HHS-0401 DM93 Y10(0.15)  LDD0267  [1]
 LDCM0120  HHS-0701 DM93 Y10(0.65)  LDD0268  [1]

References

1 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.