Details of the Target
General Information of Target
| Target ID | LDTP18745 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rho guanine nucleotide exchange factor 35 (ARHGEF35) | |||||
| Gene Name | ARHGEF35 | |||||
| Gene ID | 445328 | |||||
| Synonyms |
ARHGEF5L; Rho guanine nucleotide exchange factor 35; Rho guanine nucleotide exchange factor 5-like protein |
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| 3D Structure | ||||||
| Sequence |
MDEGMEISSEGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQS
VSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYS ALVYAINSEDTETLKVLLSACKAKGKEVIIITTAKLPCGKHTTKQYLNMPPVDIDGCHSP ATCTTPSEIDIKTASSPLSHSSETELTLFGFKDLELAGSNDDTWDPGSPVRKPALAPKGP KLPHAPPWVKSPPLLMHQNRVASLQEELQDITPEEELSYKTNGLALSKRFITRHQSIDVK DTAHLLRAFDQASSRKMSYDEINCQSYLSEGNQQCIEVPVDQDPDSNQTIFASTLRSIVQ KRNLGANHYSSDSQLSAGLTPPTSEDGKALIGKKKILSPSPSQLSESKELLENIPPGPLS RRNHAVLERRGSGAFPLDHSVTQTRQGFLPPLNVNSHPPISDINVNNKICSLLSCGQKVL MPTVPIFPKEFKSKKMLLRRQSLQTEQIKQLVNF |
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| Target Bioclass |
Other
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C186(1.33) | LDD3360 | [1] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0162 | [2] | |
|
NAIA_5 Probe Info |
 |
C458(0.00); C186(0.00) | LDD2224 | [3] | |
Competitor(s) Related to This Target
References