Details of the Target

General Information of Target

Target ID LDTP18672
Target Name Double homeobox protein B (DUXB)
Gene Name DUXB
Synonyms
Double homeobox protein B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSE
ASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSSMSEEQLSRYEVCRRSAFPRA
RVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVR
RLKPKGLFPNSNCKRIMF
Target Bioclass
Transcription factor
Family
Paired homeobox family
Subcellular location
Nucleus
Uniprot ID
A0A1W2PPF3
Ensemble ID
ENST00000633875.4
HGNC ID
HGNC:33345

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		H300(0.00); H307(0.00)  LDD0223  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa H300(0.00); H307(0.00)  LDD0223  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.