Details of the Target
General Information of Target
| Target ID | LDTP18558 | |||||
|---|---|---|---|---|---|---|
| Target Name | Pregnancy-specific beta-1-glycoprotein 8 (PSG8) | |||||
| Gene Name | PSG8 | |||||
| Gene ID | 440533 | |||||
| Synonyms |
Pregnancy-specific beta-1-glycoprotein 8; PS-beta-G-8; PSBG-8; Pregnancy-specific glycoprotein 8 |
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| 3D Structure | ||||||
| Sequence |
MATSQYFDFAQGGGPQYSAQPPTLPLPTVGASYTAQPTPGMDPAVNPAFPPAAPAGYGGY
QPHSGQDFAYGSRPQEPVPTATTMATYQDSYSYGQSAAARSYEDRPYFQSAALQSGRMTA ADSGQPGTQEACGQPSPHGSHSHAQPPQQAPIVESGQPASTLSSGYTYPTATGVQPESSA SIVTSYPPPSYNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQLPPPPAPA GSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHLGGQKHRKKEA AQKTGVQPNGSPRGVQAQLHCDLCAVSCTGADAYAAHIRGSKHQKVFKLHAKLGKPIPTL EPALATESPPGAEAKPTSPTGPSVCASSRPALAKRPVASKALCEGPPEPQAAGCRPQWGK PAQPKLEGPGAPTQGGSKEAPAGCSDAQPVGPEYVEEVFSDEGRVLRFHCKLCECSFNDL NAKDLHVRGRRHRLQYRKKVNPDLPIATEPSSRARKVLEERMRKQRHLAEERLEQLRRWH AERRRLEEEPPQDVPPHAPPDWAQPLLMGRPESPASAPLQPGRRPASSDDRHVMCKHATI YPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVAPQTRVLKGVMRVG ILAKGLLLRGDRNVRLALLCSEKPTHSLLRRIAQQLPRQLQMVTEDEYEVSSDPEANIVI SSCEEPRMQVTISVTSPLMREDPSTDPGVEEPQADAGDVLSPKKCLESLAALRHARWFQA RASGLQPCVIVIRVLRDLCRRVPTWGALPAWAMELLVEKAVSSAAGPLGPGDAVRRVLEC VATGTLLTDGPGLQDPCERDQTDALEPMTLQEREDVTASAQHALRMLAFRQTHKVLGMDL LPPRHRLGARFRKRQRGPGEGEEGAGEKKRGRRGGEGLV |
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| Target Bioclass |
Immunoglobulin
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| Family |
Immunoglobulin superfamily, CEA family
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| Subcellular location |
Secreted
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| DU145 | SNV: p.P30T; p.R293S | . | |||
| HCT15 | SNV: p.P289H | . | |||
| MDAMB453 | SNV: p.E348Q | DBIA Probe Info | |||
| MFE319 | SNV: p.S153G | . | |||
| NB1 | SNV: p.Q185H | . | |||
| NCIH1793 | SNV: p.Y210F | . | |||
| NCIH2172 | SNV: p.R345G; p.A393S | . | |||
| NCIH23 | SNV: p.P214H | . | |||
| SUIT2 | Substitution: p.P30L | . | |||
| SW756 | SNV: p.S421Y | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
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C262(3.12) | LDD2284 | [1] | |
Competitor(s) Related to This Target