Details of the Target

General Information of Target

Target ID LDTP18531
Target Name SRR1-like protein (SRRD)
Gene Name SRRD
Gene ID 402055
Synonyms
SRR1L; SRR1-like protein; SRR1 domain-containing protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTY
HDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEML
PPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKLSG
LTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERP
ILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPG
KLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQESCE
SPDVLDRHQTMEVSC
Target Bioclass
Other
Family
SRR1 family
Subcellular location
Cytoplasm
Function Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes.
Uniprot ID
Q9UH36
Ensemble ID
ENST00000215917.11
HGNC ID
HGNC:33910

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C137(0.96)  LDD1507  [1]
IPM
 Probe Info  		N.A.  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C137(0.96)  LDD1507  [1]
 LDCM0276  AC17 HEK-293T C137(0.95)  LDD1515  [1]
 LDCM0285  AC25 HEK-293T C137(0.93)  LDD1524  [1]
 LDCM0294  AC33 HEK-293T C137(0.92)  LDD1533  [1]
 LDCM0303  AC41 HEK-293T C137(0.98)  LDD1542  [1]
 LDCM0311  AC49 HEK-293T C137(1.00)  LDD1550  [1]
 LDCM0320  AC57 HEK-293T C137(0.97)  LDD1559  [1]
 LDCM0356  AKOS034007680 HEK-293T C137(0.99)  LDD1570  [1]
 LDCM0367  CL1 HEK-293T C137(1.01)  LDD1571  [1]
 LDCM0370  CL101 HEK-293T C137(1.00)  LDD1574  [1]
 LDCM0374  CL105 HEK-293T C137(0.99)  LDD1578  [1]
 LDCM0378  CL109 HEK-293T C137(1.00)  LDD1582  [1]
 LDCM0383  CL113 HEK-293T C137(1.00)  LDD1587  [1]
 LDCM0387  CL117 HEK-293T C137(0.99)  LDD1591  [1]
 LDCM0392  CL121 HEK-293T C137(1.04)  LDD1596  [1]
 LDCM0396  CL125 HEK-293T C137(1.02)  LDD1600  [1]
 LDCM0400  CL13 HEK-293T C137(1.01)  LDD1604  [1]
 LDCM0404  CL17 HEK-293T C137(1.03)  LDD1608  [1]
 LDCM0413  CL25 HEK-293T C137(1.05)  LDD1617  [1]
 LDCM0417  CL29 HEK-293T C137(0.86)  LDD1621  [1]
 LDCM0426  CL37 HEK-293T C137(1.02)  LDD1630  [1]
 LDCM0431  CL41 HEK-293T C137(0.92)  LDD1635  [1]
 LDCM0439  CL49 HEK-293T C137(1.05)  LDD1643  [1]
 LDCM0440  CL5 HEK-293T C137(0.99)  LDD1644  [1]
 LDCM0444  CL53 HEK-293T C137(1.00)  LDD1647  [1]
 LDCM0453  CL61 HEK-293T C137(1.04)  LDD1656  [1]
 LDCM0457  CL65 HEK-293T C137(1.00)  LDD1660  [1]
 LDCM0466  CL73 HEK-293T C137(1.08)  LDD1669  [1]
 LDCM0470  CL77 HEK-293T C137(1.08)  LDD1673  [1]
 LDCM0479  CL85 HEK-293T C137(1.08)  LDD1682  [1]
 LDCM0483  CL89 HEK-293T C137(0.97)  LDD1686  [1]
 LDCM0492  CL97 HEK-293T C137(1.14)  LDD1695  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019