Details of the Target
General Information of Target
| Target ID | LDTP18520 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rab-like protein 2A (RABL2A) | |||||
| Gene Name | RABL2A | |||||
| Gene ID | 11159 | |||||
| Synonyms |
Rab-like protein 2A |
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| 3D Structure | ||||||
| Sequence |
MPNPKNSKGGRKNKRANSSGDEQENGAGALAAAGAAGAAAGGALAAAAGCGAAAAGAPGA
GGAAGAGGAGTGAANAAAAAGAAAAGDAKNEAPCATPLICSFGRPVDLEKDDYQKVVCNN EHCPCSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCRQNMWTKKGYDLAFRFCSCRC GQGHLKKDTDWYQVKRMQDEKKKKSGSEKNTGRPPGEAAEEAKKCRPPNKPQKGPSHDLP RRHSMDRQNSQEKAVGAAAYGARSPGGSPGQSPPTGYSILSPAHFSGPRSSRYLGEFLKN AIHLEPHKKAMAGGHVFRNAHFDYSPAGLAVHRGGHFDTPVQFLRRLDLSELLTHIPRHK LNTFHVRMEDDAQVGQGEDLRKFILAALSASHRNVVNCALCHRALPVFEQFPLVDGTLFL SPSRHDEIEYDVPCHLQGRLMHLYAVCVDCLEGVHKIICIKCKSRWDGSWHQLGTMYTYD ILAASPCCQARLNCKHCGKPVIDVRIGMQYFSEYSNVQQCPHCGNLDYHFVKPFSSFKVL EAY |
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| Target Bioclass |
Enzyme
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| Family |
Small GTPase superfamily, Rab family
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| Function |
Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
STPyne Probe Info |
 |
K150(10.00) | LDD0277 | [1] | |
|
Acrolein Probe Info |
 |
N.A. | LDD0222 | [2] | |
|
4-Iodoacetamidophenylacetylene Probe Info |
 |
N.A. | LDD0038 | [3] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0036 | [3] | |
|
Lodoacetamide azide Probe Info |
 |
N.A. | LDD0037 | [3] | |
|
IPM Probe Info |
 |
C26(0.00); C128(0.00) | LDD2156 | [4] | |
|
AOyne Probe Info |
 |
12.80 | LDD0443 | [5] | |
Competitor(s) Related to This Target
The Interaction Atlas With This Target
References