Details of the Target
General Information of Target
| Target ID | LDTP18497 | |||||
|---|---|---|---|---|---|---|
| Target Name | Zinc finger protein 226 (ZNF226) | |||||
| Gene Name | ZNF226 | |||||
| Gene ID | 7769 | |||||
| Synonyms |
Zinc finger protein 226 |
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| 3D Structure | ||||||
| Sequence |
MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITC
PCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNS FKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGSTYKKTFLGSSLVDWLISNSFTASRLEA VTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKISPKEEISLS TVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSL VSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT |
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| Target Bioclass |
Transcription factor
|
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| Family |
Krueppel C2H2-type zinc-finger protein family
|
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| Subcellular location |
Nucleus
|
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| Function | May be involved in transcriptional regulation. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| HCC15 | Insertion: p.G288RfsTer21 | . | |||
| HEC1 | SNV: p.N43S | DBIA Probe Info | |||
| HS578T | SNV: p.L658F | . | |||
| HT | SNV: p.R113K | . | |||
| LNCaP clone FGC | SNV: p.D187N | . | |||
| MCC26 | SNV: p.H329Y | . | |||
| MEWO | SNV: p.S191F | . | |||
| NCIH1155 | SNV: p.C645Y | . | |||
| NCIH2291 | Insertion: p.T771KfsTer33 | . | |||
| NCIH23 | Substitution: p.R513I | . | |||
| PATU8988T | SNV: p.S376F | . | |||
| SNU449 | SNV: p.C290R | . | |||
| SUPT1 | SNV: p.A320T | . | |||
| THP1 | SNV: p.C337F | . | |||
| UACC257 | Substitution: p.H493Y | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C354(1.79) | LDD3409 | [1] | |
|
IA-alkyne Probe Info |
 |
C354(0.02) | LDD2214 | [2] | |
|
CY-1 Probe Info |
 |
N.A. | LDD0246 | [3] | |
Competitor(s) Related to This Target
References