Details of the Target

General Information of Target

Target ID LDTP18490
Target Name Sarcoma antigen 1 (SAGE1)
Gene Name SAGE1
Gene ID 55511
Synonyms
SAGE; Sarcoma antigen 1; Cancer/testis antigen 14; CT14
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSDLRITEAFLYMDYLCFRALCCKGPPPARPEYDLVCIGLTGSGKTSLLSKLCSESPDNV
VSTTGFSIKAVPFQNAILNVKELGGADNIRKYWSRYYQGSQGVIFVLDSASSEDDLEAAR
NELHSALQHPQLCTLPFLILANHQDKPAARSVQEIKKYFELEPLARGKRWILQPCSLDDM
DALKDSFSQLINLLEEKDHEAVRM
Target Bioclass
Enzyme
Uniprot ID
Q9NXZ1
Ensemble ID
ENST00000324447.8
HGNC ID
HGNC:30369

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C82(0.84)  LDD3386  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A101D C82(2.22)  LDD2250  [1]
 LDCM0023  KB03 A101D C82(1.99)  LDD2667  [1]
 LDCM0024  KB05 OVK-18 C82(0.84)  LDD3386  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840