Details of the Target
General Information of Target
| Target ID | LDTP18453 | |||||
|---|---|---|---|---|---|---|
| Target Name | Neuritin (NRN1) | |||||
| Gene Name | NRN1 | |||||
| Gene ID | 51299 | |||||
| Synonyms |
NRN; Neuritin |
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| 3D Structure | ||||||
| Sequence |
MGSRCAKLNTGQSPGHSPGHSTGHGRGHESSMKKLMACVSQDNFSLSSAGEEEEEEEEEG
EEEEKEELPVQGKLLLLEPERQEEGHKDNAEAQQSPEPKRTPS |
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| Target Type |
Literature-reported
|
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| Target Bioclass |
Other
|
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| Family |
Neuritin family
|
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| Subcellular location |
Cell membrane
|
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| Function | Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
C31(0.54) | LDD2229 | [1] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0166 | [2] | |
|
Lodoacetamide azide Probe Info |
 |
N.A. | LDD0037 | [3] | |
References