Details of the Target

General Information of Target

Target ID LDTP18434
Target Name Placenta-specific protein 1 (PLAC1)
Gene Name PLAC1
Gene ID 10761
Synonyms
Placenta-specific protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSPVDASSADGGSGLGSHRRKRTTFSKGQLLELERAFAAWPYPNISTHEHLAWVTCLPE
AKVQVWFQKRWAKIIKNRKSGILSPGSECPQSSCSLPDTLQQPWDPQMPGQPPPSSGTPQ
RTSVCRHSSCPAPGLSPRQGWEGAKAVAPWGSAGASEVHPSLERATPQTSLGSLSDLIYA
LAIVVNVDHS
Target Type
Literature-reported
Target Bioclass
Other
Family
PLAC1 family
Subcellular location
Secreted
Function May play a role in placental development.
TTD ID
T29712
Uniprot ID
Q9HBJ0
DrugMap ID
TTM18HX
Ensemble ID
ENST00000359237.9
HGNC ID
HGNC:9044

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C80(0.29)  LDD2182  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0625  F8 Ramos C80(1.07)  LDD2187  [1]
 LDCM0572  Fragment10 Ramos C80(0.28)  LDD2189  [1]
 LDCM0573  Fragment11 Ramos C80(0.33)  LDD2190  [1]
 LDCM0574  Fragment12 Ramos C80(0.58)  LDD2191  [1]
 LDCM0575  Fragment13 Ramos C80(0.56)  LDD2192  [1]
 LDCM0576  Fragment14 Ramos C80(2.85)  LDD2193  [1]
 LDCM0579  Fragment20 Ramos C80(0.29)  LDD2194  [1]
 LDCM0582  Fragment23 Ramos C80(0.83)  LDD2196  [1]
 LDCM0578  Fragment27 Ramos C80(0.76)  LDD2197  [1]
 LDCM0586  Fragment28 Ramos C80(0.59)  LDD2198  [1]
 LDCM0588  Fragment30 Ramos C80(1.64)  LDD2199  [1]
 LDCM0590  Fragment32 Ramos C80(0.76)  LDD2201  [1]
 LDCM0468  Fragment33 Ramos C80(0.87)  LDD2202  [1]
 LDCM0566  Fragment4 Ramos C80(0.90)  LDD2184  [1]
 LDCM0610  Fragment52 Ramos C80(0.51)  LDD2204  [1]
 LDCM0614  Fragment56 Ramos C80(0.52)  LDD2205  [1]
 LDCM0569  Fragment7 Ramos C80(1.08)  LDD2186  [1]
 LDCM0571  Fragment9 Ramos C80(0.72)  LDD2188  [1]
 LDCM0022  KB02 Ramos C80(0.29)  LDD2182  [1]
 LDCM0023  KB03 Ramos C80(1.05)  LDD2183  [1]
 LDCM0024  KB05 Ramos C80(0.60)  LDD2185  [1]

References

1 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578