General Information of Target

Target ID LDTP18430
Target Name Zinc finger protein 556 (ZNF556)
Gene Name ZNF556
Gene ID 80032
Synonyms
Zinc finger protein 556
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNRKKLQKLTDTLTKNCKHFNKFEVNCLIKLFYDLVGGVERQGLVVGLDRNAFRNILHVT
FGMTDDMIMDRVFRGFDKDNDGCVNVLEWIHGLSLFLRGSLEEKMKYCFEVFDLNGDGFI
SKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFADYELAVREETLL
LEAFGPCLPDPKSQMEFEAQVFKDPNEFNDM
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9HAH1
Ensemble ID
ENST00000307635.3
HGNC ID
HGNC:25669

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C436(2.07)  LDD3401  [1]
IA-alkyne
 Probe Info 
C151(0.00); C765(0.00); C124(0.00)  LDD0161  [2]
IPM
 Probe Info 
C242(0.00); C436(0.00)  LDD0147  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Hep 3B2.1-7 C242(3.69)  LDD2353  [1]
 LDCM0023  KB03 Hep-G2 C242(17.02)  LDD2771  [1]
 LDCM0024  KB05 RD C436(2.07)  LDD3401  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255