Details of the Target

General Information of Target

Target ID LDTP18422
Target Name Uncharacterized protein C14orf93 (C14orf93)
Gene Name C14orf93
Gene ID 60686
Synonyms
Uncharacterized protein C14orf93
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MREKSFQCNESGKAFNCSSLLKKCQIIHLGEKKYKCDICGKVFNQKRYLAYHHRCHTGEK
PYKCNQCGKTFSYKSSLVIHKAIHTGEKPHKCNECGKVFNQKAYLASHHRLHTGEKPYKC
EECDKVFSR
Target Bioclass
Other
Subcellular location
Secreted
Uniprot ID
Q9H972
Ensemble ID
ENST00000299088.11
HGNC ID
HGNC:20162

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HEC1B SNV: p.P251H .
TE10 SNV: p.A72V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C522(2.76); C523(2.76)  LDD0080  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 HCT 116 C522(2.76); C523(2.76)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C522(2.12); C523(2.12)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C522(2.97); C523(2.97)  LDD0082  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.