Details of the Target

General Information of Target

Target ID	LDTP18383
Target Name	Homeobox protein Nkx-2.4 (NKX2-4)
Gene Name	NKX2-4
Gene ID	644524
Synonyms	NKX2D; Homeobox protein Nkx-2.4; Homeobox protein NK-2 homolog D
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRIT DLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDA QKVTRQEREEALVRGVFMKVVKPKASSEDVASSPERHYTPLPSASRELTSHQGVLGKCRY VYYGKNSEGNRFIRDDQL
Target Bioclass	Transcription factor
Family	NK-2 homeobox family
Subcellular location	Nucleus
Function	Probable transcription factor.
Uniprot ID	Q9H2Z4
Ensemble ID	ENST00000351817.5
HGNC ID	HGNC:7837

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
m-APA Probe Info			13.81	LDD0403	[1]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0156	Aniline	NCI-H1299	13.81	LDD0403	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor

Click To Hide/Show 1 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Homeobox protein notochord (NOTO)				.	A8MTQ0

References

1	Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.