Details of the Target

General Information of Target

Target ID LDTP18312
Target Name EF-hand calcium-binding domain-containing protein 11 (EFCAB11)
Gene Name EFCAB11
Gene ID 90141
Synonyms
C14orf143; EF-hand calcium-binding domain-containing protein 11
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTS
CLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLS
QRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPF
LMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHILARESLRQLRHLPNHS
VVKLRNAGHACYLHKPQDFHLVLLAFLDHLP
Target Bioclass
Other
Uniprot ID
Q9BUY7
Ensemble ID
ENST00000316738.12
HGNC ID
HGNC:20357

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AU565 SNV: p.D140N .
MEWO SNV: p.P69S .
NCIH1944 SNV: p.K117E .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aldo-keto reductase family 1 member B1 (AKR1B1) Aldo/keto reductase family P15121
Mitochondrial peptide methionine sulfoxide reductase (MSRA) MsrA Met sulfoxide reductase family Q9UJ68

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060