Details of the Target

General Information of Target

Target ID LDTP18291
Target Name BPI fold-containing family A member 3 (BPIFA3)
Gene Name BPIFA3
Gene ID 128861
Synonyms
C20orf71; SPLUNC3; BPI fold-containing family A member 3; Short palate, lung and nasal epithelium carcinoma-associated protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MFGGPGPGVLGAQGMAGPLRGRVEELKLPWWRESSPLVLRHSEAARLAADALLERGEAAY
LRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEASGPDRLSLLSEVTSGTYFPMA
SDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIF
TDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYC
SKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCL
YAESQPVEGFCGGEDPLSPRALRPPPVALAFRPDVPSPTSSLPSSTSLSSIKQSPLMGRS
SYLALPGGGDCSDTGVVSSSLGPARREASGQPSLHRQLSDPNHGSPPGLYRANLGKLGAY
PWSQSSPALNHNSTSPLTLAVGSPLLPRSRPLLQFHRGAPALSRFPENGLPGSQEPSPLR
GRWVPGTTLETVEEKEKKASPSQSRGQLDLLVPFPRAREVGDPDSGVTPNSGPLRPGEQA
PEDRRLSPSQADSQLDLLSRALGTGGAPELGSLRPGDRALEDRRLSLNQSRGQSDLLMQY
PKAQGSRVPLETNSSARPARRAPDERRQTLGHSQLDLITKFGPFRGEGPGPNGLPISSPA
RTAGAGSGDEKRLTLGHSKLDLITKYHQLHGARQGTEPGGPKGGHLNGGNSDLVRDEKRL
TLGHSKLDLITKYNKSKFKQLRSRFES
Target Bioclass
Other
Family
BPI/LBP/Plunc superfamily, Plunc family
Subcellular location
Secreted
Uniprot ID
Q9BQP9
Ensemble ID
ENST00000375452.3
HGNC ID
HGNC:16204

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO792 SNV: p.S130F .
IGR1 SNV: p.M185I .
LN18 SNV: p.N191K .
MOLT4 SNV: p.M203T .
RPMI8226 SNV: p.P4A .
SW948 SNV: p.M2L .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060