Details of the Target

General Information of Target

Target ID LDTP18231
Target Name Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 (AGAP4)
Gene Name AGAP4
Gene ID 119016
Synonyms
AGAP8; CTGLF1; CTGLF5; MRIP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4; AGAP-4; Centaurin-gamma-like family member 1; Centaurin-gamma-like family member 5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQ
RQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIH
FTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARREL
DIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDL
DSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARC
SAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMP
EALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKG
KLIYKT
Target Bioclass
Other
Family
Centaurin gamma-like family
Function Putative GTPase-activating protein.
Uniprot ID
Q96P64
Ensemble ID
ENST00000448048.7
HGNC ID
HGNC:23459

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ATP probe
 Probe Info  		N.A.  LDD0199  [1]

References

1 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.