Details of the Target

General Information of Target

Target ID	LDTP18225
Target Name	Zinc finger protein 285 (ZNF285)
Gene Name	ZNF285
Gene ID	26974
Synonyms	ZNF285A; Zinc finger protein 285; Zinc finger protein 285A
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MAVGLLKAMYQELVTFRDVAVDFSQEEWDCLDSSQRHLYSNVMLENYRILVSLGLCFSKP SVILLLEQGKAPWMVKRELTKGLCSGWEPICETEELTPKQDFYEEHQSQKIIETLTSYNL EYSSLREEWKCEGYFERQPGNQKACFKEEIITHEEPLFDEREQEYKSWGSFHQNPLLCTQ KIIPKEEKVHKHDTQKRSFKKNLMAIKPKSVCAEKKLLKCNDCEKVFSQSSSLTLHQRIH TGEKPYKCIECGKAFSQRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEK PYECKVCRKAFSQFAYLAQHQRVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYEC NVCGKAFSLRAYLTVHQRIHTGERPYECKECGKAFSQNSHLAQHQRIHTGEKPYKCQECR KAFSQIAYLAQHQRVHTGEKPYECIECGKAFSNDSSLTQHQRVHTGEKPYECTVCGKAFS YCGSLAQHQRIHTGERPYECKECKKTFRQHAHLAHHQRIHIGESLSPPNPVNHQVL
Target Bioclass	Transcription factor
Family	Krueppel C2H2-type zinc-finger protein family
Subcellular location	Nucleus
Function	May be involved in transcriptional regulation.
Uniprot ID	Q96NJ3
Ensemble ID	ENST00000544719.6
HGNC ID	HGNC:13079

Target Site Mutations in Different Cell Lines

Cell line	Mutation details	Probe for labeling this protein in this cell
GB1	SNV: p.A557D	.
HT115	SNV: p.V529A	.
KMCH1	SNV: p.Q5P	.
KYSE180	SNV: p.G168R	.
MCC13	SNV: p.G168E	.
MELJUSO	SNV: p.Q567E	.
MEWO	SNV: p.M1?; p.E20K; p.E158K; p.E341K	.
MIAPACA2	Substitution: p.S186N; p.C190H	.
OVK18	SNV: p.S99A	.
SUPT1	SNV: p.P229Q	.

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
Acrolein Probe Info			N.A.	LDD0230	[1]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0109	NEM	HeLa	N.A.	LDD0230	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other

Click To Hide/Show 1 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Caspase recruitment domain-containing protein 10 (CARD10)				.	Q9BWT7

References

1	ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.