Details of the Target

General Information of Target

Target ID LDTP18208
Target Name RIPOR family member 3 (RIPOR3)
Gene Name RIPOR3
Gene ID 140876
Synonyms
C20orf175; C20orf176; FAM65C; RIPOR family member 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAWAGSRRVPAGTRAAAERCCRLSLSPGAQPAPPPGPLPPPRPMRFLTSCSLLLPRAAQI
LAAEAGLPSSRSFMGFAAPFTNKRKAYSERRIMGYSMQEMYEVVSNVQEYREFVPWCKKS
LVVSSRKGHLKAQLEVGFPPVMERYTSAVSMVKPHMVKAVCTDGKLFNHLETIWRFSPGI
PAYPRTCTVDFSISFEFRSLLHSQLATMFFDEVVKQNVAAFERRAATKFGPETAIPRELM
FHEVHQT
Target Bioclass
Enzyme
Family
RIPOR family
Uniprot ID
Q96MK2
Ensemble ID
ENST00000045083.6
HGNC ID
HGNC:16168

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K82(0.45)  LDD0277  [1]
DBIA
 Probe Info  		C648(2.01); C706(1.86)  LDD2252  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A204 C648(2.01); C706(1.86)  LDD2252  [2]
 LDCM0023  KB03 A204 C648(1.60); C706(1.96)  LDD2669  [2]
 LDCM0024  KB05 A204 C648(1.63); C706(1.36)  LDD3086  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840