Details of the Target

General Information of Target

Target ID LDTP18165
Target Name Zinc finger protein 486 (ZNF486)
Gene Name ZNF486
Gene ID 90649
Synonyms
KRBO2; Zinc finger protein 486; KRAB domain only protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQP
SVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLY
FLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITAN
KNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIK
MEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q96H40
Ensemble ID
ENST00000335117.9
HGNC ID
HGNC:20807

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C87(1.03)  LDD2157  [1]
HHS-465
 Probe Info  		K348(0.00); K351(0.00); K404(0.00); K407(0.00)  LDD2240  [2]

References

1 From chemoproteomic-detected amino acids to genomic coordinates: insights into precise multi-omic data integration. Mol Syst Biol. 2021 Feb;17(2):e9840. doi: 10.15252/msb.20209840.
Mass spectrometry data entry: PXD022151
2 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010