General Information of Target

Target ID LDTP18162
Target Name X antigen family member 2 (XAGE2)
Gene Name XAGE2
Gene ID 9502
Synonyms
GAGED3; XAGE2B; X antigen family member 2; XAGE-2; Cancer/testis antigen 12.2; CT12.2; G antigen family D member 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLVSGRRRLLTVLLQAQKWPFQPSRDMRLVQFRAPHLVGPHLGLETGNGGGVINLNAFDP
TLPKTMTQFLEQGEATLSVARRALAAQLPVLPRSEVTFLAPVTRPDKVVCVGMNYVDHCK
EQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELAVVIGKKGKHIKATDAMA
HVAGFTVAHDVSARDWQMRRNGKQWLLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVN
GEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQ
CEIEELGVIINKVV
Target Bioclass
Other
Family
GAGE family
Uniprot ID
Q96GT9
Ensemble ID
ENST00000286049.3
HGNC ID
HGNC:4112

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C82(1.11)  LDD2260  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A-549 C82(1.11)  LDD2260  [1]
 LDCM0023  KB03 HCC15 C82(1.05)  LDD2757  [1]
 LDCM0024  KB05 ABC-1 C82(1.69)  LDD3096  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840