General Information of Target

Target ID LDTP18077
Target Name Netrin-5 (NTN5)
Gene Name NTN5
Gene ID 126147
Synonyms
Netrin-5; Netrin-1-like protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIWRGRSTYRPRPRRSVPPPELIGPMLEPGDEEPQQEEPPTESRDPAPGQEREEDQGAAE
TQVPDLEADLQELSQSKTGGECGNGPDDQGKILPKSEQFKMPEGGDRQPQV
Target Bioclass
Other
Subcellular location
Secreted
Function Plays a role in neurogenesis. Prevents motor neuron cell body migration out of the neural tube.
Uniprot ID
Q8WTR8
Ensemble ID
ENST00000270235.11
HGNC ID
HGNC:25208

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.L432M .
MEWO SNV: p.P101S .
MOLT4 SNV: p.T329I .
NCIH23 SNV: p.R120K .
OCUM1 SNV: p.D406Y .
PC9 SNV: p.G284R .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ENE
 Probe Info 
N.A.  LDD0006  [1]

References

1 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764