Details of the Target

General Information of Target

Target ID LDTP18018
Target Name Olfactory receptor 6X1 (OR6X1)
Gene Name OR6X1
Gene ID 390260
Synonyms
Olfactory receptor 6X1; Olfactory receptor OR11-270
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDTSTSVTYDSSLQISQFILMGLPGIHEWQHWLSLPLTLLYLLALGANLLIIITIQHETV
LHEPMYHLLGILAVVDIGLATTIMPKILAIFWFDAKAISLPMCFAQIYAIHCFFCIESGI
FLCMAVDRYIAICRPLQYPSIVTKAFVFKATGFIMLRNGLLTIPVPILAAQRHYCSRNEI
EHCLCSNLGVISLACDDITVNKFYQLMLAWVLVGSDMALVFSSYAVILHSVLRLNSAEAM
SKALSTCSSHLILILFHTGIIVLSVTHLAEKKIPLIPVFLNVLHNVIPPALNPLACALRM
HKLRLGFQRLLGLGQDVSK
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family
Subcellular location
Cell membrane
Function Odorant receptor.
Uniprot ID
Q8NH79
Ensemble ID
ENST00000327930.3
HGNC ID
HGNC:14737

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C305(1.02)  LDD1701  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0023  KB03 MDA-MB-231 C305(1.02)  LDD1701  [1]

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761