Details of the Target

General Information of Target

Target ID LDTP18003
Target Name Olfactory receptor 52N1 (OR52N1)
Gene Name OR52N1
Gene ID 79473
Synonyms
Olfactory receptor 52N1; Olfactory receptor OR11-61
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEQHNLTTVNEFILTGITDIAELQAPLFALFLMIYVISVMGNLGMIVLTKLDSRLQTPMY
FFLRHLAFMDLGYSTTVGPKMLVNFVVDKNIISYYFCATQLAFFLVFIGSELFILSAMSY
DLYVAICNPLLYTVIMSRRVCQVLVAIPYLYCTFISLLVTIKIFTLSFCGYNVISHFYCD
SLPLLPLLCSNTHEIELIILIFAAIDLISSLLIVLLSYLLILVAILRMNSAGRQKAFSTC
GAHLTVVIVFYGTLLFMYVQPKSSHSFDTDKVASIFYTLVIPMLNPLIYSLRNKDVKYAL
RRTWNNLCNIFV
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family
Subcellular location
Cell membrane
Function Odorant receptor.
Uniprot ID
Q8NH53
Ensemble ID
ENST00000641645.1
HGNC ID
HGNC:14853

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY-1
 Probe Info  		D315(0.00); H318(0.00)  LDD0246  [1]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.