Details of the Target

General Information of Target

Target ID LDTP17997
Target Name Olfactory receptor 6S1 (OR6S1)
Gene Name OR6S1
Gene ID 341799
Synonyms
Olfactory receptor 6S1; Olfactory receptor OR14-37
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDIPQNITEFFMLGLSQNSEVQRVLFVVFLLIYVVTVCGNMLIVVTITSSPTLASPVYFF
LANLSFIDTFYSSSMAPKLIADSLYEGRTISYECCMAQLFGAHFLGGVEIILLTVMAYDR
YVAICKPLHNTTIMTRHLCAMLVGVAWLGGFLHSLVQLLLVLWLPFCGPNVINHFACDLY
PLLEVACTNTYVIGLLVVANSGLICLLNFLMLAASYIVILYSLRSHSADGRCKALSTCGA
HFIVVALFFVPCIFTYVHPFSTLPIDKNMALFYGILTPMLNPLIYTLRNEEVKNAMRKLF
TW
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family
Subcellular location
Cell membrane
Function Odorant receptor.
Uniprot ID
Q8NH40
Ensemble ID
ENST00000320704.3
HGNC ID
HGNC:15363

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C84(4.52)  LDD3311  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A2058 C84(1.81)  LDD2253  [1]
 LDCM0023  KB03 A2058 C84(3.51)  LDD2670  [1]
 LDCM0024  KB05 G361 C84(4.52)  LDD3311  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840