Details of the Target

General Information of Target

Target ID LDTP17935
Target Name Olfactory receptor 10Q1 (OR10Q1)
Gene Name OR10Q1
Gene ID 219960
Synonyms
Olfactory receptor 10Q1; Olfactory receptor OR11-233
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKTLCSFLQISRNMHQENQTTITEFILLGLSNQAEHQNLLFVLFLSMYVVTVVGNGLIIV
AISLDIYLHTPMYLFLAYLSFADISSISNSVPKMLVNIQTNSQSISYESCITQMYFSIVF
VVTDNLLLGTMAFDHFVAICHPLNYTTFMRARFGTLLTVISWFLSNIIALTHTLLLIQLL
FCDHNTLPHFFCDLAPLLKLSCSDTMINELVLFIVGLSVIIFPFVLIFFSYVCIIRAVLG
VSSTQGKWKAFSTCGSHLTIALLFYGTTVGVYFFPSSTHPEDTDKIGAVLFTVVTPMMNP
FIYSLRNKDMKGALRKLINRKISSL
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family
Subcellular location
Cell membrane
Function Odorant receptor.
Uniprot ID
Q8NGQ4
Ensemble ID
ENST00000316770.2
HGNC ID
HGNC:15134

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C407(5.04)  LDD3427  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Hs 936.T C407(3.00)  LDD2363  [1]
 LDCM0023  KB03 IGR-1 C407(5.87)  LDD2812  [1]
 LDCM0024  KB05 SK-MEL-28 C407(5.04)  LDD3427  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840