Details of the Target

General Information of Target

Target ID LDTP17790
Target Name Uncharacterized protein C3orf20 (C3orf20)
Gene Name C3orf20
Gene ID 84077
Synonyms
Uncharacterized protein C3orf20
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSKGKDKKKGKSKGKDTKKLIKTDESVVDRAKANASLWEARLEVTELSRIKYRDTSRIL
AKSNEDLKKKQCKMEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQK
YTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVERELDDLKENLRNTERIHQET
LRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKENDYLQKALAYHL
KETDALQKNSQKLQESHTLLLHQKEINDLLVKEKIMQLVQQRSQIQTLQKKVVNLETALS
YMTKEFESEVLKLQQHAMIENQAGQVEIDKLQHLLQMKDREMNRVKKLAKNILDERTEVE
RFFLDALHQVKQQILISRKHYKQIAQAAFNLKMRAACTGRTEYPKIRTFDGREHSTNSVN
QDLLEAEKWTHIEGNVDIGDLTWEQKEKVLRLLFAKMNGCPSRKYNQSSRPPVPDYVVSD
SGETKEFGDESKLQDKIFITQQIAISDSSGEVVLPTIPKEPQESDTGTF
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
Q8ND61
Ensemble ID
ENST00000253697.8
HGNC ID
HGNC:25320

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CMK SNV: p.L311F .
HCC15 SNV: p.G682C .
HSC3 SNV: p.T84P .
IM95 SNV: p.P100A .
MEWO SNV: p.P770L .
NCIH2172 SNV: p.I25T .
OVCAR8 Deletion: p.K367RfsTer69
SNV: p.H461R		 .
OVK18 SNV: p.S464N; p.P628T .
PC9 Insertion: p.G449RfsTer6
SNV: p.G449C		 .
SNU1 SNV: p.K250N .
SW1271 SNV: p.G197V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K805(6.34)  LDD0277  [1]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270