Details of the Target

General Information of Target

Target ID LDTP17707
Target Name Spermatogenesis associated 6-like protein (SPATA6L)
Gene Name SPATA6L
Gene ID 55064
Synonyms
C9orf68; Spermatogenesis associated 6-like protein
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAAGTAARKAAPVLEAPPQQEQLSHTKLSAEDTWNLQQERMYKMHRGHDSMHVEMILIFL
CVLVIAQIVLVQWRQRHGRSYNLVTLLQMWVVPLYFTIKLYWWRFLSMWGMFSVITSYIL
FRATRKPLSGRTPRLVYKWFLLIYKLSYAFGVVGYLAIMFTMCGFNLFFKIKARDSMDFG
IVSLFYGLYYGVMGRDFAEICSDYMASTIGFYSVSRLPTRSLSDNICAVCGQKIIVELDE
EGLIENTYQLSCNHVFHEFCIRGWCIVGKKQTCPYCKEKVDLKRMISNPWERTHFLYGQI
LDWLRYLVAWQPVVIGIVQGIIYSLGLE
Target Bioclass
Other
Family
SPATA6 family
Uniprot ID
Q8N4H0
Ensemble ID
ENST00000406861.6
HGNC ID
HGNC:25472

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
KYSE410 SNV: p.P321S .
LNCaP clone FGC SNV: p.N362S .
LS180 SNV: p.T319A .
MCC13 SNV: p.P327L .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060