Details of the Target
General Information of Target
| Target ID | LDTP17696 | |||||
|---|---|---|---|---|---|---|
| Target Name | Protein PHTF2 (PHTF2) | |||||
| Gene Name | PHTF2 | |||||
| Gene ID | 57157 | |||||
| Synonyms |
Protein PHTF2 |
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| 3D Structure | ||||||
| Sequence |
MFCHLRPMRRLCLEKIFPHWFPFSRALSGAEAVNALRPFYFAVHPDFFGQHPVEREINEN
SLKRLSVYLENLQKPGFKSLKPTQLTFYVRETDQSSSDGQEPFSTSGFRAVKFTLHTRDL LSTVLYILNSCSLSVEHIQSLNTNMHTQPLKEAKRMPDRPIKWDKSYYSFTGFKDPDEDL EQVSRVETTLTSWLDNNGKSAVKKLKNSLPLRKELDRLKDELSHQLQLSDIRWQRSWGIA HRCSQLHSLSRLAQQNLETLKKAKGCTIIFTDRSGMSAVGHVMLGTMDVHHHWTKLFERL PSYFDLQRRLMILEDQISYLLGGIQVVYIEELQPVLTLEEYYSLLDVFYNRLLKSRILFH PRSLRGLQMILNSDRYAPSLHELGHFNIPTLCDPANLQWFILTKAQQARENMKRKEELKV IENELIQASTKKFSLEKLYKEPSISSIQMVDCCKRLLEQSLPYLHGMHLCISHFYSVMQD GDLCIPWNWKNGEAIK |
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| Target Bioclass |
Transcription factor
|
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| Subcellular location |
Membrane
|
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| 8505C | SNV: p.H365N | . | |||
| AGS | SNV: p.Y34H | . | |||
| EFO27 | SNV: p.N432I | . | |||
| EGI1 | SNV: p.W781Ter | DBIA Probe Info | |||
| HCT15 | SNV: p.S393Y | . | |||
| HT115 | SNV: p.K79N; p.D351G | . | |||
| JURKAT | SNV: p.V153I | . | |||
| KMCH1 | SNV: p.V725L | . | |||
| MCC13 | SNV: p.L280F | DBIA Probe Info | |||
| MEWO | SNV: p.W140G | . | |||
| MFE319 | Insertion: p.L570FfsTer10 | . | |||
| NCIH1048 | Insertion: p.L570FfsTer10 | . | |||
| RKO | SNV: p.Q629H | . | |||
| THP1 | SNV: p.W251R | . | |||
| UACC62 | SNV: p.P433L | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C382(1.39) | LDD3325 | [1] | |
Competitor(s) Related to This Target