Details of the Target

General Information of Target

Target ID LDTP17680
Target Name Putative inactive cytochrome P450 family member 4Z2 (CYP4Z2P)
Gene Name CYP4Z2P
Synonyms
Putative inactive cytochrome P450 family member 4Z2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSALWLLLGLLALMDLSESSNWGCYGNIQSLDTPGASCGIGRRHGLNYCGVRASERLAEI
DMPYLLKYQPMMQTIGQKYCMDPAVIAGVLSRKSPGDKILVNMGDRTSMVQDPGSQAPTS
WISESQVSQTTEVLTTRIKEIQRRFPTWTPDQYLRGGLCAYSGGAGYVRSSQDLSCDFCN
DVLARAKYLKRHGF
Target Bioclass
Enzyme
Family
Cytochrome P450 family
Subcellular location
Membrane
Uniprot ID
Q8N1L4
HGNC ID
HGNC:24426

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY-1
 Probe Info  		T276(0.00); T277(0.00)  LDD0246  [1]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.