Details of the Target

General Information of Target

Target ID LDTP17645
Target Name EF-hand calcium-binding domain-containing protein 13 (EFCAB13)
Gene Name EFCAB13
Gene ID 124989
Synonyms
C17orf57; EF-hand calcium-binding domain-containing protein 13
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEASVDASTLPVTVKKKKSLSIEEKIDIINAVESGKKKAEIAAEYGIKKNSLSSIMKNK
DKVLEAFESLRFDPKRKRLRTAFYTDLEEALMRWYRIAQCLNVPVNGPMLRLKANDFAQK
LGHNDFKCSNGWLDRFKSRYGLVFRAQPVEATGVPVDPSTVWYQNVLPYYLNDYHPKNVF
NIKETGLLYRMLPTNTFAFKGETCSVGKLCKDRITLVVGTNMDGSEKLPLLVIGKKRTPH
CFKGLKSLPVCYEANRMAWMTSDVFEQWMRKLDEEFQAQQRRVVIFVESFPAHPEVKNLK
SIELAFFPSCLSSKCIAMKQGVIKSLKIKYRHCLIKKFLSSVEGSKEFTFSLLDAVDTLH
LCWRAVTPETIVKSYEEAGFKSQKGESDITNAEKDTGLDLVADALGAGVEFPEGLSIEEY
AALDDDLETCEAAPNGDSICTKESKSDETGFYTSDEEDDDGSPGTELPLPSKSEAITALD
TLKKFLRSQDMNDGLQNSLADLENFINSLSPK
Target Bioclass
Other
Uniprot ID
Q8IY85
Ensemble ID
ENST00000331493.7
HGNC ID
HGNC:26864

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 SNV: p.E83G; p.I886V .
COLO792 SNV: p.L457V .
HCT15 SNV: p.E509A .
HT115 SNV: p.D306N; p.K368Q; p.K411E .
IGROV1 SNV: p.I46T; p.P434S .
IM95 Deletion: p.K635RfsTer5 .
Ishikawa (Heraklio) 02 ER Deletion: p.N362IfsTer5
SNV: p.E83G		 .
KMRC1 Deletion: p.D421EfsTer16 .
KMRC20 SNV: p.I253V .
MCC13 SNV: p.S335F .
MDAMB453 SNV: p.D780H .
SNU1 SNV: p.A173V .
TCCSUP SNV: p.A680D .
TKKK SNV: p.I253V .
YSCCC SNV: p.E520K .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.