Details of the Target

General Information of Target

Target ID LDTP17637
Target Name Aquaporin-12A (AQP12A)
Gene Name AQP12A
Gene ID 375318
Synonyms
AQP12; AQPX2; Aquaporin-12A; AQP-12
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
METQNLTVVTEFILLGLTQSQDAQLLVFVLVLIFYLIILPGNFLIIFTIKSDPGLTAPLY
FFLGNLALLDASYSFIVVPRMLVDFLSEKKVISYRSCITQLFFLHFLGAGEMFLLVVMAF
DRYIAICRPLHYSTIMNPRACYALSLVLWLGGFIHSIVQVALILHLPFCGPNQLDNFFCD
VPQVIKLACTNTFVVELLMVSNSGLLSLLCFLGLLASYAVILCRIREHSSEGKSKAISTC
TTHIIIIFLMFGPAIFIYTCPFQAFPADKVVSLFHTVIFPLMNPVIYTLRNQEVKASMRK
LLSQHMFC
Target Bioclass
Transporter and channel
Family
MIP/aquaporin (TC 1.A.8) family, AQP11/AQP12 subfamily
Subcellular location
Membrane
Function Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Uniprot ID
Q8IXF9
Ensemble ID
ENST00000337801.9
HGNC ID
HGNC:19941

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060