Details of the Target

General Information of Target

Target ID LDTP17631
Target Name Protein FAM219A (FAM219A)
Gene Name FAM219A
Gene ID 203259
Synonyms
C9orf25; Protein FAM219A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNETNKTLVGPSELPTASAVAPGPGTGARAWPVLVGFVLGAVVLSLLIALAAKCHLCRRY
HASYRHRPLPETGRGGRPQVAEDEDDDGFIEDNYIQPGTGELGTEGSRDHFSL
Target Bioclass
Other
Family
FAM219 family
Uniprot ID
Q8IW50
Ensemble ID
ENST00000297620.8
HGNC ID
HGNC:19920

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A431 SNV: p.E16D .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C32(1.01)  LDD1492  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 HEK-293T C32(1.01)  LDD1492  [1]
 LDCM0023  KB03 HEK-293T C32(1.02)  LDD1497  [1]
 LDCM0024  KB05 HEK-293T C32(0.98)  LDD1502  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402