Details of the Target

General Information of Target

Target ID LDTP17619
Target Name Uncharacterized protein KIAA0825 (KIAA0825)
Gene Name KIAA0825
Gene ID 285600
Synonyms
C5orf36; Uncharacterized protein KIAA0825
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEDSPLPDLRDIELKLGRKVPESLVRSLRGEEPVPRERDRDPCGGSGGGGGGGGGCSSSS
SYCSFPPSLSSSSSSSPTSGSPRGSHSSALERLETKLHLLRQEMVNLRATDVRLMRQLLV
INESIESIKWMIEEKATITSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVG
SYLDTLADDVPGHQTPSDLDQFSDSSLIEDSQALHKRPKLDSEYYCFG
Target Bioclass
Other
Uniprot ID
Q8IV33
Ensemble ID
ENST00000329378.7
HGNC ID
HGNC:28532

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C1052(1.01); C1054(1.01)  LDD1511  [1]
IPM
 Probe Info  		N.A.  LDD2156  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0281  AC21 HEK-293T C1052(0.71); C1054(0.71)  LDD1520  [1]
 LDCM0289  AC29 HEK-293T C1052(0.70); C1054(0.70)  LDD1528  [1]
 LDCM0298  AC37 HEK-293T C1052(0.81); C1054(0.81)  LDD1537  [1]
 LDCM0307  AC45 HEK-293T C1052(1.09); C1054(1.09)  LDD1546  [1]
 LDCM0312  AC5 HEK-293T C1052(0.77); C1054(0.77)  LDD1551  [1]
 LDCM0316  AC53 HEK-293T C1052(0.77); C1054(0.77)  LDD1555  [1]
 LDCM0325  AC61 HEK-293T C1052(0.99); C1054(0.99)  LDD1564  [1]
 LDCM0248  AKOS034007472 HEK-293T C1052(1.01); C1054(1.01)  LDD1511  [1]
 LDCM0409  CL21 HEK-293T C1052(0.45); C1054(0.45)  LDD1613  [1]
 LDCM0422  CL33 HEK-293T C1052(0.39); C1054(0.39)  LDD1626  [1]
 LDCM0435  CL45 HEK-293T C1052(0.38); C1054(0.38)  LDD1639  [1]
 LDCM0448  CL57 HEK-293T C1052(0.42); C1054(0.42)  LDD1651  [1]
 LDCM0461  CL69 HEK-293T C1052(0.44); C1054(0.44)  LDD1664  [1]
 LDCM0475  CL81 HEK-293T C1052(0.52); C1054(0.52)  LDD1678  [1]
 LDCM0484  CL9 HEK-293T C1052(0.46); C1054(0.46)  LDD1687  [1]
 LDCM0488  CL93 HEK-293T C1052(0.49); C1054(0.49)  LDD1691  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Optineurin (OPTN) . Q96CV9
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019