Details of the Target

General Information of Target

Target ID LDTP17570
Target Name Mas-related G-protein coupled receptor member E (MRGPRE)
Gene Name MRGPRE
Gene ID 116534
Synonyms
GPR167; MRGE; Mas-related G-protein coupled receptor member E; G-protein coupled receptor 167
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MFGLFGLWRTFDSVVFYLTLIVGLGGPVGNGLVLWNLGFRIKKGPFSIYLLHLAAADFLF
LSCRVGFSVAQAALGAQDTLYFVLTFLWFAVGLWLLAAFSVERCLSDLFPACYQGCRPRH
ASAVLCALVWTPTLPAVPLPANACGLLRNSACPLVCPRYHVASVTWFLVLARVAWTAGVV
LFVWVTCCSTRPRPRLYGIVLGALLLLFFCGLPSVFYWSLQPLLNFLLPVFSPLATLLAC
VNSSSKPLIYSGLGRQPGKREPLRSVLRRALGEGAELGARGQSLPMGLL
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family, Mas subfamily
Subcellular location
Cell membrane
Function Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Uniprot ID
Q86SM8
Ensemble ID
ENST00000389832.7
HGNC ID
HGNC:30694
ChEMBL ID
CHEMBL4523882

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0161  [1]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060