General Information of Target

Target ID LDTP17569
Target Name Mas-related G-protein coupled receptor member G (MRGPRG)
Gene Name MRGPRG
Gene ID 386746
Synonyms
GPR169; MRGG; Mas-related G-protein coupled receptor member G; G-protein coupled receptor 169
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVAPAARVFLRAVRAALTSTVPDLLCLLARGSPRGLASGRLPLAVHSAQHGPGSGAPWLR
IARRALRFVLSKHWGDDCYLTNRLWQDLKPPSHVENGQELRLAPPVQWALQVQGNQLQTA
VLCLRMAPPEPAGSRQRI
Target Bioclass
GPCR
Family
G-protein coupled receptor 1 family, Mas subfamily
Subcellular location
Cell membrane
Function Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Uniprot ID
Q86SM5
Ensemble ID
ENST00000332314.3
HGNC ID
HGNC:24829
ChEMBL ID
CHEMBL4523881

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Phosphinate-6
 Probe Info 
N.A.  LDD0018  [1]

References

1 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004