Details of the Target
General Information of Target
| Target ID | LDTP17549 | |||||
|---|---|---|---|---|---|---|
| Target Name | Chemokine-like protein TAFA-3 (TAFA3) | |||||
| Gene Name | TAFA3 | |||||
| Gene ID | 284467 | |||||
| Synonyms |
FAM19A3; Chemokine-like protein TAFA-3 |
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| 3D Structure | ||||||
| Sequence |
MDNRNTQMYTEEEKTVNPFLPSTPGPKKAKGGGEAVETHPAPGPLPPPEVRDIGERREPD
RAQQQPQKPAVAAGTQSLGNFRQGFMKCLLEVEKMEASHRRASKARSQTAQKSPRTLTPV PTSAPSLPQTPASVPASGPSWARLPAPGPEPAPMGAPVPTSMPCPVLLGPALDLGWRRME LLHQSSERTLSYAKARQEPEEQSLQKLYQNREKSEEQLTLKQEEAFRSYFEIFNGPGEVD AQSLKNILLLMGFSVTLAQVEDALMSADVNGDGRVDFKDFLAVMTDTRRFFCSVEQNALS DMAPHNPHTLLFEILSLLVEMLALPEAVLEEITNYYQKKLKEGTCKAQEMEAAVGRLRLQ KLPYNPQQEESSEVPERKVLSILSRLKQQNYAPNLQSPYAQVPCILLCPQLDKKMVRRQP SNHYALDQCTPPGLDPDIRSPFFQSGSQGNREHNSDSRKWLSSVPARTH |
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| Target Bioclass |
Cytokine and receptor
|
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| Family |
TAFA family
|
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| Subcellular location |
Secreted
|
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| Function | Plays a role in the regulation of microglia polarization. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| GB2 | SNV: p.M100I | . | |||
| SKNAS | SNV: p.M100I | DBIA Probe Info | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C96(3.78) | LDD3311 | [1] | |
Competitor(s) Related to This Target